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劉振洋教授:2023 ESMO WCGIC精彩回顧,胃癌靶向治療迎來新突破

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湖南省腫瘤醫(yī)院消化泌尿內(nèi)一科主任

主任醫(yī)師,醫(yī)學(xué)博士,博士后

湖南省醫(yī)學(xué)會(huì)消化腫瘤內(nèi)科學(xué)組組長

湖南省抗癌協(xié)會(huì)腫瘤靶向治療專委會(huì)主任委員

湖南省抗癌協(xié)會(huì)大腸癌專委會(huì)副主任委員

湖南省抗癌協(xié)會(huì)家族遺傳性腫瘤專委會(huì)副主任委員

湖南省醫(yī)促會(huì)惡性腫瘤精準(zhǔn)與綜合診療專委會(huì)副主任委員

[2]L. Shen, D. Liu, N. Li,et al. Osemitamab in combination with capecitabine and oxaliplatin (CAPOX) as a first line treatment of advanced G/GEJ cancer: Updated data of cohort C from a phase I/IIa, multi-center study (TranStar102/TST001-1002). 2023 ESMO WCGIC. Abstract PD-7.[3]Z. Wainberg, Y. Kang, K. Lee, et al. Bemarituzumab for treatment of previously untreated advanced and/or metastatic gastric and gastroesophageal cancer (GC): Final analysis of a randomized phase 2 trial (FIGHT). 2023 ESMO WCGIC. Abstract SO-11.[4]T. Satoh, P. Barthélémy, L. Nogova, et al. Phase 2 Study of Futibatinib in Patients With Specific FGFR Aberrations: Activity in Patients With Gastric or Gastroesophageal Junction Cancer Harboring FGFR2 Amplification. 2023 ESMO WCGIC. Abstract SO-10.[5]Bang YJ, Van Cutsem E, Feyereislova A, et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet. 2010 Aug 28;376(9742):687-97.[6]Hofheinz R , Hegewischbecker S , Thusspatience P C , et al. HER-FLOT: Trastuzumab in combination with FLOT as perioperative treatment for patients with HER2-positive locally advanced esophagogastric adenocarcinoma: A phase II trial of the AIO Gastric Cancer Study Group.2014 ASCO. Abstract 4073.[7]Shitara K, Lordick F, Bang YJ, et al. Zolbetuximab + mFOLFOX6 as first-line (1L) treatment for patients (pts) with claudin-18.2+ (CLDN18.2+) / HER2? locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary results from phase 3 SPOTLIGHT study. 2023 ASCO GI. Abstract LBA292.[8]Xu Rh, Shitara K, Ajani JA, Zolbetuximab + CAPOX in 1L claudin-18.2+ (CLDN18.2+)/HER2? locally advanced (LA) or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Primary phase 3 results from GLOW. 2023 ASCO GI. Abstract 405736.[9]Kohei Shitara, Rui-Hua Xu, Diarmuid Martin Moran, et al. Global prevalence of CLDN18.2 in patients with locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Biomarker analysis of two zolbetuximab phase 3 studies (SPOTLIGHT and GLOW). 2023 ASCO. Abstract 4035.本材料由阿斯利康提供,僅供醫(yī)療衛(wèi)生專業(yè)人士進(jìn)行醫(yī)學(xué)科學(xué)交流,不用于推廣目的審批編號(hào):CN-120160 過期日期:2024-2-9

* 此文僅用于向醫(yī)學(xué)人士提供科學(xué)信息,不代表本平臺(tái)觀點(diǎn)

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